Preserving Lean Muscle Mass: GLP-1 therapy, while aiding in weight loss, may lead to the loss of lean muscle mass due to a decrease in nutritional intake from a reduced appetite
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Moreover, this effect of L-carnitine on protein synthesis was consistent with that of protein expression, mitochondrial function, and cell survival (Figure 5), suggesting that these deleterious effects of lenvatinib were primarily caused by its inhibitory action on protein synthesis
However, SAXENDA remains a well-established choice with a longer history of use and a flexible dosing regimen that may suit certain patients better